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- and of local lymph nodes in 10 to 30 percent. In over half the cases with lymph node involvement, distant metastases are found.
- In over 40 percent of patients, the symptoms that cause them to seek medical attention are due to metastases.
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- What Causes It Risk factors are poorly defined, although the incidence is twice as high for those using tobacco (cigars, chewing tobacco, cigarettes).
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